It's Garry Shandling's Show (1986)

Creator: Garry Shandling

Garry Shandling stars as himself, a neurotic, sardonic stand-up comedian who just happens to be aware he is a sitcom character. Garry spends just as much time interacting with the studio audience as he does the regular cast members, performing monologues and show-closing summations of the episode's events. However, everyone knows they're on TV, not just Garry; and the audience (itself a character) is often involved in the storyline.

Cast

Garry Shandling

Garry Shandling

Molly Cheek

Nancy Bancroft

Jessica Harper

Phoebe Bass

Scott Nemes

Grant Schumaker

Michael Tucci

Pete Schumaker